Moreover, the low-oxygen condition called hypoxia worsens mitochondrial damage and promotes the formation of the fatty deposits that can progress to cirrhosis. 此外,低氧条件下缺氧恶化称为线粒体损伤和促进脂肪沉积,可进展为肝硬化的形成。
Cusi said nonalcoholic fatty liver disease probably accounts for about half of the people who develop cirrhosis of the liver. Cusi认为非酒精性脂肪肝可能为约一半肝硬化患者的病因。
Detection and significance of Leptin and its receptors in experimental fatty liver and cirrhosis of liver 实验性脂肪肝、肝硬化中Leptin及其受体的检测与表达意义
An estimated two-thirds of obese people have some form of fatty liver, including nonalcoholic steatohepatitis ( NASH), which can progress to cirrhosis and subsequently HCC. 据估计三分之二的肥胖人群有不同程度的脂肪肝,包括非酒精性脂肪性肝炎(NASH),其可以进展为肝硬化和肝细胞癌。
Non-alcoholic fatty liver disease can result in cirrhosis of the liver or liver cancer. 非酒精性脂肪肝病能够导致肝硬化或肝癌。
Objective To explore the relationship between incidence of fatty liver, cirrhosis, gallstone and other bodily diseases in alcoholism mental disorder patient with the drinking period and drinking quantity. 目的利用超声征像探讨超声诊断酒精所致精神障碍伴发脂肪肝、肝硬化、胆结石等躯体疾病患者发病率与饮酒年限、饮酒量之间的关系。
Objective To observe the changes of serum leptin, the expression of the leptin receptors in the liver of experimental fatty liver and hepatic cirrhosis, and to discuss the possible mechanisms and significance. 目的观察Leptin在实验性脂肪肝与肝硬化大鼠血清水平及其受体在肝脏免疫组化表达和定位情况,探讨Leptin及其受体在实验性脂肪肝与肝硬化发生病理机制中的作用。
Fatty liver is as a high risk factor of the PHC as chronic hepatopathy or HBV infection and cirrhosis. 脂肪肝和慢性肝炎、HBV感染及肝硬化一样同属原发性肝癌的高危人群。
Research on Tyrosine Phosphorylation of Leptin Receptors in Experimental Fatty Liver and Hepatic Cirrhosis 实验性大鼠脂肪肝及肝硬化瘦素受体蛋白酪氨酸磷酸化研究
Results: fatty liver and hepatic cirrhosis models were successfully induced. 结果:脂肪肝及肝硬化模型复制成功。
CONCLUSIONS Maotai may lead to fatty liver but not obvious hepatic fibrosis and cirrhosis, and strengthen lipid peroxidation in liver. 结论茅台酒可致脂肪肝但不引起明显的肝纤维化及肝硬化,有增加肝脏的脂质抗氧化作用。
A high speed digital data acquisition and wide band measurement system was used to acquire and record the ultrasonic pulse waveforms backscattered from normal and several pathological pig's fresh liver tissues ( including ballooning degeneration, fatty degeneration, cirrhosis) in vitro. 本文采用宽带超声脉冲测量系统,通过对散射回波高速数字采样,对猪的新鲜离体正常肝组织及若干病变肝组织(如水泡变性肝,脂肪变性肝及硬化肝)进行了分析研究。
Conclusion: The CT appearances of chronic alcoholic toxic cerebral injuries and liver injuries were cerebral atrophy in different degree, encephalomalacia foci, fatty liver, liver cirrhosis. 结论:慢性酒精中毒性脑病、肝病的CT表现特点是不同程度的脑萎缩、脑软化灶、脂肪肝、肝硬化。
The OD value of of leptin receptor in rat hepatic tissu was significantly decreased in fatty group compared with the hepatic cirrhosis group and the control ( P < 0.01). 脂肪肝组Leptin受体酪氨酸磷酸化蛋白表达降低,其光密度值与正常组及肝硬化组比较差异在统计学上均有显著差异(P<0.01);
ALF is the intermediary from minor alcoholic liver disease, alcoholic fatty, alcoholic hepatitis to alcoholic liver cirrhosis. For its reversibility, it has been one of the hotspots in the present studies. 酒精性肝纤维化是轻症酒精性肝病、酒精性脂肪肝、酒精性肝炎、酒精性肝纤维化向酒精性肝硬化发展的必经之路,具有可逆性,研究肝纤维化的形成机制是当前研究的热点之一。
The Expression of Leptin Receptors Gene in Experimental Fatty Liver and Cirrhosis of Liver Leptin受体在实验性脂肪肝及肝硬化中基因表达的研究
Some cases may progress to fatty hepatitis and cirrhosis. 部分脂肪肝可发展为脂肪性肝炎、肝硬化。
Objective: The incidence of Non-alcoholic fatty liver ( nonalcoholic fatty liver disease, NAFLD) increased year by year, and the disease can progress to liver fibrosis and cirrhosis, but its precise mechanism is currently unclear. 目的:非酒精性脂肪肝(Nonalcoholicfattyliverdisease,NAFLD)发病率逐年增高,且有进展到肝纤维化肝硬化的趋势,目前其确切的发病机制尚不清楚。
Evaluation and control of diseases were related to the progress and prognosis of chronic hepatic diseases, especially for viral hepatitis, alcoholic hepatic disease, hepatic disease in schistosomiasis, fatty liver and etc, an irreversible progress to the hepatic cirrhosis would happen without treating promptly. 尤其是病毒性肝炎、酒精性肝病、血吸虫性肝病、脂肪肝等慢性肝病,慢性肝纤维化的过程若未得到及时控制,将进一步进展为难以逆转的肝硬化失代偿期。
The classical clinical manifestations of ALD are alcoholic fatty liver, alcoholic hepatitis and alcoholic liver fibrosis, which even can become inconvertible alcoholic cirrhosis. 典型的酒精性肝病临床表现为脂肪肝、酒精性肝炎、酒精性肝纤维化,最终将发展为不可逆性肝硬化。
Purpose: Alcoholic liver disease, ALD is a pathological change caused by excessive intake of ethanol or alcohol which causes liver damage, which can develop from fatty degeneration to an advanced stage of the disease, such as, cirrhosis even liver cancer. 目的酒精性肝病(alcoholicliverdisease,ALD)是由于身体摄取过量乙醇即酒精,导致的肝脏受损,轻则从脂肪变性进阶到的肝硬化甚则肝癌其阶段性病变。
Result: Histopathology revealed serious fatty degeneration of liver, fatty liver and the onset of hepatitis, fibrosis and cirrhosis. Along with the time progress, in islet gradually atrophic and accompanied by inflammatory infiltration. Fat cells gradually increased and with inflammatory infiltration. 结果:病理组织学显示肝脏发生严重的脂变、脂肪肝进而发生肝炎、纤维化及肝硬化;随时间进展胰岛逐渐萎缩并伴有炎性浸润;脂肪细胞逐渐增大并伴有炎性浸润。
Background& Purpose: Hyperlipidemic fatty liver disease ( HFLD) is one kind of non-alcoholic fatty liver disease. The simple steatosis may develop to steatohepatitis, liver fibrosis or cirrhosis. 背景和目的:高脂性脂肪肝是非酒精性脂肪肝的一种类型,它从单纯性脂肪变性可能发展为脂肪性肝炎、肝纤维化甚至肝硬化。